Studies on Chemotherapeutics XXVI

Xxvi . Studies on the Interaction . of Amino - Compounds and Carbohydrates

A CRYSTALLINE condensation product of glucose and urea was first described by Schoorl [1900, 1, 2; 1903]. So thorough did the last communication appear to be, that, apart from the synthesis of glucose ureide accomplished by Fischer [1914], the condensation of glucose and urea does not seem to have been further investigated. As indicated in the previous paper [Hynd, 1926], it was found difficult...

Studies of drugs given before anaesthesia XXVI: lorazepam.

Lorazepam has been studied as preanaesthetic medication given by mouth, i.m. and i.v. Sediation and side-effects and the incidence of anterograde amnesia in patients having a standard operation under methohexitone-nitrous oxide-oxygen anaesthesia were assessed. In a preliminary study of three i.m. (2-, 4- and 8-mg) and six oral (1-,2-,2.5-,4-,5- and 8-mg) doses, the optimum dose was found to be...

XXVI. STUDIES ON THE POLYMERIC 1\SATURE OF THE CORTICOSTEROID~RINDING GLOBULInT OF THE RABBIT*

The rabbit corticosteroid-binding globulin (CBG), fully saturated with corticosteroid, was separated by Sephadex G-ZOO filtration into a corticoid-binding monomer and a steroid-free tetramer. Polymerization could be enhanced by removal of the steroid from CBG or by prolonged storage. Partial depolymerization and reactivation of the inactive tetramer was obtained by incubation with a relatively ...

Studies in steroid metabolism. XXVI. Steroid isolation studies in human leukemia.

STUDIES ON ENZYMATIC HISTOCHEMISTRY XXVI. Tm~ HISTOLOGICAL DISTRIBUTION O1~ CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY

In previous papers of this series Linderstr¢fm-Lang, Holter, and coworkers have investigated the histological distribution of pepsin (1, 2), acid (2, 3), peptidase (2, 4), and esterase (2, 5) in the gastric mucosa of pigs, and the urease (6) in dog's stomach. The present investigation is a continuation of this work with regard to choline esterase. In view of the well known theory of chemical me...